I have been running this for nearly a week. In general you get the best results on a machine that has a decent video card so it can do the computations in the GPU instead of the CPU. There are different projects that they support - not all of the work units are covid related, but the covid ones seem to run in the GPU.
Laptops are probably a poor choice. If you have a PC that was set up for gaming, it is probably a good choice.
